The evolution of the MUC7 gene, which encodes a saliva protein, was studied by scientists at the University at Buffalo. To capture the gene’s proline-, threonine-, and serine-rich tandem repeat copy ...
Various approaches have been developed to identify and quantitate copy-number variation. A new, high-resolution approach that already shows promise is digital PCR. As illustrated by many research ...
SNF-CLIMEDIN: A Randomized Trial of Digital Support and Intervention in Patients With Advanced Non–Small Cell Lung Cancer. A Hellenic Cooperative Oncology Group Study Shallow whole-genome sequencing ...
SMBE Journals (Molecular Biology and Evolution and Genome Biology and Evolution) Generating genome sequence data from six additional C. psl. strains that differed markedly in the size of their genomes ...
Accurate prediction of CYP2D6 activity from genotype data is of utmost importance as CYP2D6 pharmacogenetic (PGx) testing is increasingly used to guide drug therapy. However, given the complexity of ...
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Retrotransposons and their role in human genetic disorders
Retrotransposons are pivotal in human genome evolution, driving structural variation and regulatory innovation while influencing health and disease.
Genome assemblies from 65 individuals, representing a variety of the world’s populations, are advancing the scientific exploration of complex genetic structural variation. Structural variations are ...
Genetic ancestry plays a key role in determining the behavior of head and neck tumors and may help explain why African-American patients survive for half as long as their counterparts of European ...
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