Impact of BRCA1 gene alterations on tumor characteristics and clinical outcome in ovarian cancer (OC) patients. Background: Advanced ovarian clear cell carcinomas (OCCCs) are notoriously drug ...
Dissecting complex genetic and epigenetic alterations in cancer genomes using CpG island microarrays
We describe a high-throughput approach for investigating both copy number alterations and aberrant methylation of CpG islands in human cancer. The technique involves generation of a microarray panel ...
Gene amplification is one of the major mechanisms of oncogene activation in tumorigenesis. Currently, however, direct identification of amplified genes in cancer remains difficult. The most important ...
With the April 2005 release of its Little Dipper Microarray Processing System, Sunnyvale, Calif.-based SciGene has now completed its benchtop system for automated microarray processing from ...
Impact of insulin-like growth factor 1 receptor (IGF1R) and amphiregulin (AREG) expressions on survival in patients with stage II/III gastric cancer enrolled in the ACTS-GC study. Multivariate ...
The Geniom® RT Analyzer, a new benchtop microarray processing instrument, was presented by febit at Select Bioscience’s “Advances in Microarray Technology”. The platform complements Geniom® One, the ...
While microarray technology is broadening its applications in genomics and proteomics, the technique remains a vibrant contributor in the area of gene expression. Much of the overall developmental ...
In this issue we take a close look at DNA microarrays, the current amore of biological and biomedical researchers. There's little reason to doubt that the infatuation will continue, at least for ...
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