In a two-color experiment (panel a in the figure) DNA from individuals of the same species or different tissue from a single individual (e.g., normal and diseased cells) is extracted and ...

Microarray-based methods for the study of pathogenic bacteria. (a) Comparative genomic hybridization compares the chromosomal DNA content of two related strains. Genomic DNA is isolated from two ...

Hybridization, washing, staining, and scanning protocols for the HG-U133 Plus 2.0 microarrays were performed on Affymetrix GeneChip instruments (Hybridization Oven 640, Fluidics Station FS450, Scanner ...

The Geniom® RT Analyzer, a new benchtop microarray processing instrument, was presented by febit at Select Bioscience’s “Advances in Microarray Technology”. The platform complements Geniom® One, the ...

Serial analysis of gene expression (SAGE) uses mRNA from a sample to create complementary DNA (cDNA) fragments for amplification and sequencing using high-throughput sequencing technology. Credit: ...

In each type of cell, like a muscle cell or a skin cell, different genes are expressed (turned on) or silenced (turned off). If the cells that are turned on mutate, they could—depending on what role ...

With the April 2005 release of its Little Dipper Microarray Processing System, Sunnyvale, Calif.-based SciGene has now completed its benchtop system for automated microarray processing from ...

In this issue we take a close look at DNA microarrays, the current amore of biological and biomedical researchers. There's little reason to doubt that the infatuation will continue, at least for ...

While microarray technology is broadening its applications in genomics and proteomics, the technique remains a vibrant contributor in the area of gene expression. Much of the overall developmental ...

To prevent outbreaks of water- or food-borne illnesses, scientists need rapid, sensitive methods to detect pathogenic bacteria such as Escherichia coli, Salmonella enterica, and Campylobacter jejuni.

Microarrays provide a way of organizing biological samples for high-throughput analysis. Samples are arranged in columns and rows upon a support surface consisting of a glass slide, a nitrocellulose ...