A wave of spatial transcriptomics studies has produced gene-expression atlases that span entire organs and whole organisms, ...

Fei Chen and Chenlei Hu at the Broad Institute of MIT and Harvard have developed a new imaging-free spatial transcriptomics technology that tracks the diffusion of DNA barcodes between beads in an ...

Foundation models (FMs), which are deep learning models pretrained on large-scale data and applied to diverse downstream ...

A team of researchers has constructed the most detailed single-cell map of the adult human prostate to date, cataloging more ...

A new spatial transcriptomic approach captures the regulation of splicing and polyadenylation sites during pubescent brain development at near-single-cell resolution. An international collaboration, ...

Larotrectinib in Patients With Tumors With NTRK Fusions: Results From the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol EAY131-Z1E Advancements in profiling technologies have deepened our ...

Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context. In musculoskeletal ...

Digital spatial profiling (DSP) is emerging as a powerful technology in helping specialists investigate complex kidney ...