http://www.bing.com:80/search?q=JSON-RPC+vs+RestSearch resultshttp://www.bing.com:80/s/a/rsslogo.gifhttp://www.bing.com:80/search?q=JSON-RPC+vs+RestCopyright © 2026 Microsoft. All rights reserved. These XML results may not be used, reproduced or transmitted in any manner or for any purpose other than rendering Bing results within an RSS aggregator for your personal, non-commercial use. Any other use of these results requires express written permission from Microsoft Corporation. By accessing this web page or using these results in any manner whatsoever, you agree to be bound by the foregoing restrictions.https://www.uptodate.com/contents/glucagon-like-peptide-1-based-therapies-for-the-treatment-of-type-2-diabetes-mellitusGlucagon-like peptide 1 (GLP-1)-based therapies (eg, GLP-1 receptor agonists, dual-acting GLP-1 and glucose-dependent insulinotropic polypeptide [GIP] receptor agonists) affect glycemia through several mechanisms, including increased glucose-dependent insulin secretion, slowed gastric emptying, and reduced food intake and postprandial glucagon ...Wed, 19 Aug 2026 18:31:00 GMThttps://sso.uptodate.com/contents/searchAccess UpToDate's comprehensive medical database for reliable, evidence-based clinical information and guidelines.Sat, 22 Aug 2026 23:50:00 GMThttps://www.uptodate.com/contents/alcohol-use-disorder-pharmacologic-managementExplore pharmacologic management strategies for alcohol use disorder, including treatment options and outcomes, on this comprehensive resource.Fri, 21 Aug 2026 00:57:00 GMThttps://sso.uptodate.com/contents/idiopathic-intracranial-hypertension-pseudotumor-cerebri-prognosis-and-treatment/printA pressure-lowering effect of GLP-1 agonists is also supported by animal models, where exenatide decreased CSF secretion by the choroid plexus in rats with hydrocephalus [29].Fri, 21 Aug 2026 21:28:00 GMThttps://ff.uptodate.com/contents/nonselective-nsaids-overview-of-adverse-effectsThe side effects that can occur following the use of nonselective NSAIDs (nsNSAIDs) that block both cyclooxygenase (COX)-1 and COX-2 will be reviewed here. The side effects associated with the selective COX-2 inhibitors are discussed separately.Fri, 21 Aug 2026 12:31:00 GMThttps://sjr.uptodate.com/contents/whats-new-in-drug-therapyGlucagon-like peptide 1 (GLP-1)-based agents are efficacious for weight loss but may lead to disproportionate loss of muscle mass. In a systematic review of 35 studies evaluating the effect of GLP-1-based medications on body composition, almost 30 percent of weight loss from these agents was attributable to reductions in muscle-based indices [17].Sun, 23 Aug 2026 01:59:00 GMThttps://www.uptodate.com/contents/idiopathic-intracranial-hypertension-pseudotumor-cerebri-prognosis-and-treatmentEffects on symptoms and vision outcomes were not evaluated. A pressure-lowering effect of GLP-1 agonists is also supported by animal models, where exenatide decreased CSF secretion by the choroid plexus in rats with hydrocephalus [29]. Among GLP-1 agonists, exenatide is seldom used as it requires frequent dosing.Sun, 16 Aug 2026 21:48:00 GMThttps://www.uptodate.com/contents/initial-management-of-hyperglycemia-in-adults-with-type-2-diabetes-mellitusImproved glycemic management lowers the risk of microvascular complications in patients with type 2 diabetes (figure 1) [1]. Every 1 percent drop in glycated hemoglobin (A1C) is associated with improved outcomes over the long term with no threshold effect.Thu, 30 Jul 2026 13:33:00 GMThttps://www.uptodate.com/contents/whats-new-in-primary-careGlucagon-like peptide 1 (GLP-1)-based agents are efficacious for weight loss but may lead to disproportionate loss of muscle mass. In a systematic review of 35 studies evaluating the effect of GLP-1-based medications on body composition, almost 30 percent of weight loss from these agents was attributable to reductions in muscle-based indices [26].Thu, 20 Aug 2026 17:40:00 GMThttps://www.uptodate.com/contents/alpha-glucosidase-inhibitors-for-treatment-of-diabetes-mellitusIn addition, the transfer of polysaccharides to the more distal small intestine increases the secretion of glucagon-like peptide 1 (GLP-1) and several other gut hormones [1]. In older patients with type 2 diabetes, acarbose may also increase insulin sensitivity [2], although this may have been a nonspecific effect associated with improved glycemia.Sun, 16 Aug 2026 21:41:00 GMT