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  1. Adrenoleukodystrophy (ALD) - Johns Hopkins Medicine

    What is ALD? Adrenoleukodystrophy (ALD) is a genetic condition that damages the membrane (myelin sheath) that covers nerve cells in the brain and spinal cord. Myelin acts as insulation around …

  2. Adrenoleukodystrophy - Wikipedia

    Adrenoleukodystrophy (ALD) is a disease linked to the X chromosome. It is a result of fatty acid buildup caused by failure of peroxisomal fatty acid beta oxidation which results in the accumulation of very …

  3. Adrenoleukodystrophy (ALD): Causes, Types, Symptoms, Prognosis - WebMD

    May 22, 2024 · About 1 in 17,000 people are born with a genetic disease called adrenoleukodystrophy (ALD). This severe brain disorder mainly affects boys and men. There’s no cure yet for it, but a …

  4. Adrenoleukodystrophy - Symptoms and causes - Mayo Clinic

    Feb 7, 2020 · In adrenoleukodystrophy (ALD), your body can't break down very long-chain fatty acids (VLCFAs), causing saturated VLCFA s to build up in your brain, nervous system and adrenal gland. …

  5. ALD: Adrenoleukodystrophy, Disease, X-Linked - Cleveland Clinic

    May 17, 2021 · Adrenoleukodystrophy (ALD) is a genetic disorder. It affects the nervous system and adrenal glands. ALD symptoms include behavioral changes.

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  7. What is ALD? - The Stop ALD Foundation

    Adrenoleukodystrophy, or ALD, is an x-linked metabolic disorder, characterized by progressive neurologic deterioration due to demyelination of the cerebral white matter. Brain function declines as …

  8. Adrenoleukodystrophy (ALD) - American Brain Foundation

    Adrenoleukodystrophy (ALD) is a rare genetic disorder caused by a mutation on the X chromosome. The disease most severely affects boys, beginning between the ages of 4 and 10, although men and …

  9. Adrenoleukodystrophy (ALD) | Boston Children's Hospital

    ALD is caused by mutations in the ABCD1 gene that prevent the body from breaking down very-long-chain fatty acids (VLCFAs). As a result, VLCFAs build up in the brain, nervous system, and adrenal …

  10. Pediatric adrenoleukodystrophy (ALD) - Children's Health

    Adrenoleukodystrophy (ALD), also known as X-linked adrenoleukodystrophy (X-ALD), is a rare, genetic disorder in which the body cannot break down fatty acids in the brain.