In order to test robustness against patient-based variability in potency, two sets of Monte-Carlo simulations were run using the closed-loop vasopressor (“CLV”) controller to manage a vasopressor …

Sep 19, 2025 · This study aimed to evaluate the performance of vasopressor administration algorithms based on lower-limit control by (1) modeling blood pressure response to vasopressor administration; …

The aim of this randomised controlled study was to evaluate whether the CLV controller was superior to traditional vasopressor management at minimising hypotension in patients undergoing abdominal …

Dec 18, 2023 · In patients admitted to the ICU after high-risk abdominal surgery, closed-loop control of norepinephrine infusion better maintained a MAP target of 80 to 90 mmHg and significantly …

Because it is unfeasible for human providers to pay constant attention and make second-to-second changes, management is often suboptimal (ie, large amounts of time are spent in hypotension below …

In this simulation study, the closed-loop vasopressor controller remained effective in simulated patients exhibiting 0.1 to 10 × the expected population drug response.

In order to test robustness against patient-based variability in potency, two sets of Monte-Carlo simulations were run using the closed-loop vasopressor (“CLV”) controller to manage a vasopressor …

Apr 1, 2026 · Closed-loop vasopressor systems integrate real-time blood pressure monitoring with automated decision logic to support hemodynamic stability in perioperative and critical care …

Closed-loop vasopressor systems integrate real-time blood pressure monitoring with automated decision logic to support hemodynamic stability in perioperative and critical care environments.

Sep 13, 2023 · By providing insights into the current state of closed-loop systems for blood pressure control, this review offers a comprehensive overview of their potential contributions to improved …

Ideally, changes in vasopressor infusion rates have to quickly follow variations in blood pressure measurements. However, such a tightly controlled feedback loop is difficult to achieve.