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Myc - Wikipedia
The Myc family consists of three related human genes: c-myc (MYC), l-myc (MYCL), and n-myc (MYCN). c-myc (also sometimes referred to as MYC) was the first gene to be discovered in this …
MYC: there is more to it than cancer - PMC
MYC is a pleiotropic transcription factor involved in multiple cellular processes. While its mechanism of action and targets are not completely elucidated, it has a fundamental role in cellular proliferation, …
MYC in cancer: from undruggable target to clinical trials
Feb 19, 2025 · This Review provides an overview of the various strategies to inhibit MYC, focusing on the most recently described inhibitors and those that have reached clinical trials.
MYC Gene - GeneCards | MYC Protein | MYC Antibody
Jan 15, 2026 · MYC (MYC Proto-Oncogene, BHLH Transcription Factor) is a Protein Coding gene. Diseases associated with MYC include Burkitt Lymphoma and High-Grade B-Cell Lymphoma Double …
MYC: Master Regulator of Cell Death and Tumor Progression
Mar 14, 2025 · MYC gene has become one of the most investigated oncogenes for regulating programmed cell death and tumor growth. MYC is a transcription factor that regulates the expression …
MYC function and regulation in physiological perspective
Oct 24, 2023 · MYC levels are tightly regulated, and deregulation of MYC has been associated with numerous diseases including cancer. Understanding the comprehensive biology of MYC under …
The MYC oncogene — the grand orchestrator of cancer growth ...
MYC has two paralogues: MYCL and MYCN. The initially held view was that MYC is ubiquitously involved in human cancers (both haematological and solid), whereas L-MYC is associated with small …
MYC, Metabolism, and Cancer - PMC
The MYC oncogene encodes a transcription factor, MYC, whose broad effects make its precise oncogenic role enigmatically elusive. The evidence to date suggests that MYC triggers selective …
MYC as a target for cancer treatment - PubMed
Because of its high prevalence of deregulation and its causal role in cancer formation, maintenance and progression, targeting MYC is theoretically an attractive strategy for treating cancer.