significance implies a quality or character that should mark a thing as important but that is not self-evident and may or may not be recognized.

The discovery of the new drug is of great significance for/to people suffering from heart problems.

The significance of something is the importance that it has, usually because it will have an effect on a situation or shows something about a situation.

1. The state or quality of being significant: a matter of some significance. See Synonyms at importance. 2. A meaning that is expressed or implied: What was the significance of that smile?

significance, n. meanings, etymology, pronunciation and more in the Oxford English Dictionary

importance; consequence:the significance of the new treaty. meaning; import:The familiar place had a new significance for her. the quality of being significant or having a meaning:to give significance to …

Definition of significance. English dictionary and integrated thesaurus for learners, writers, teachers, and students with advanced, intermediate, and beginner levels.

An item's significance is a sign of its importance. The significance of something can be implicit or explicit — meaning it can be clear or only known with a deeper understanding of the situation.

Significance refers to the importance or relevance of something, often characterized by its potential impact, influence, or value. It can also refer to the measure of statistical likelihood or probability, …

Definition of significance noun in Oxford Advanced Learner's Dictionary. Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more.