Over the last decade, small-molecule microarrays (SMMs) have proven to be a general, robust and scalable screening platform for discovering protein-small molecule interactions that lead to …

Small molecule microarray (SMM) is a well-established method for identifying small molecule (SM) binding interactions with a diverse range of target types.

Feb 4, 2002 · One technique for screening small molecules uses glass slides that have been machine-printed with an array of dots, each dot containing different small molecules. This is …

In this tutorial review, we introduce small-molecule microarrays (SMMs) as an alternative general binding assay, compatible with nearly any type of protein without advanced knowledge of …

Feb 1, 2014 · Here we review the use of one such format, the small-molecule microarray (SMM), as a tool for discovering protein–small molecule interactions. This review will briefly highlight …

The chapters cover a range of small molecule library types, ranging from synthetic combinatorial libraries to peptide and carbohydrate libraries, with lessons and techniques that can be widely …

Here, we report an approach for the identification and characterization of a new class of small molecule MYC G4 ligands using small molecule microarrays (SMMs).

Small molecule microarrays are a fast, reliable, cost-effective method of compound library screening. Immobilise whole compound libraries onto functionalised slides for convenient …

Dec 22, 2005 · In this manuscript, we present a new method for the preparation and screening of small-molecule microarrays. For the first time, we demonstrate the covalent capture of natural …

New methods to identify RNA-binding small molecules open yet unexplored opportunities for the pharmacological modulation of RNA-driven biology and disease states. One such approach is …