Scalable spatial transcriptomics through computational array ...
Apr 3, 2025 · An imaging-free spatial transcriptomics method facilitates high-throughput barcode array generation up to centimeter scale.
Scaling up spatial transcriptomics for large-sized tissues ... - Nature
Sep 15, 2025 · iSCALE leverages histology and spatial transcriptomics to infer gene expression at super resolution in large tissues.
Protocol for high-resolution 3D spatial transcriptomics using Open-ST
Mar 21, 2025 · Summary Spatial transcriptomics (ST) is fundamental for understanding molecular mechanisms in health and disease. Here, we present a protocol for efficient and high-resolution ST …
Decoding cell–cell communication using spatial transcriptomics
Feb 21, 2025 · In this Tools of the Trade article, Ankit Agrawal introduces the computational framework NiCo (Niche Covariation), which integrates spatial transcriptomics with single-cell RNA-sequencing …
A visual–omics foundation model to bridge histopathology with spatial ...
May 29, 2025 · OmiCLIP is a visual–omics foundation model that integrates histology and spatial transcriptomics. The associated Loki platform offers accurate and robust tools for alignment, …
Open-ST: High-resolution spatial transcriptomics in 3D
Jul 25, 2024 · Summary Spatial transcriptomics (ST) methods unlock molecular mechanisms underlying tissue development, homeostasis, or disease. However, there is a need for easy-to-use, high …
A practical guide to spatial transcriptomics - ScienceDirect
Jun 1, 2024 · Spatial transcriptomics is revolutionizing modern biology, offering researchers an unprecedented ability to unravel intricate gene expression patterns within tissues. From pioneering …
A practical guide for choosing an optimal spatial transcriptomics ...
Jan 20, 2025 · Spatial transcriptomics technology enables the mapping of gene expression within tissues, allowing researchers to visualize the spatial distribution of RNA molecules and gain insights …
A guidebook of spatial transcriptomic technologies, data resources …
Jan 1, 2023 · Finally, we provide a detailed discussion and outlook of the spatial transcriptomic technologies, data resources and analysis approaches to guide current and future research on …
Decoding the blueprints of embryo development with single-cell and ...
Mar 1, 2025 · We deconstruct the research strategies employed by recent studies that leverage single-cell sequencing techniques and underscore the unique advantages of spatial transcriptomics.