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  1. Robust mapping of spatiotemporal trajectories and cell–cell ...

    Nov 25, 2023 · Spatial trajectory inference incorporates both gene expression and spatial information to infer the order of transcriptomes (i.e. spots or cells) along a trajectory, thereby allowing the spatio ...

  2. Topological velocity inference from spatial transcriptomic data

    Jul 16, 2025 · Here we propose Topological Velocity Inference (TopoVelo), a model for jointly inferring spatial and temporal dynamics of cell fate transition from spatial transcriptomic data.

  3. Single-cell and Spatial Transcriptomics Reveals the Spatiotemporal ...

    2 days ago · Single-cell and Spatial Transcriptomics Reveals the Spatiotemporal Trajectory of the Small Peptide TAP4 in Delaying Postharvest Fruit Senescence

  4. SIRV: spatial inference of RNA velocity at the single-cell resolution

    Aug 6, 2024 · We developed a computational method to transfer RNA velocities from scRNA-seq data to spatial transcriptomics data at the single-cell level, allowing the investigation of differentiation …

  5. Sep 4, 2023 · Abstract 2 The integration of cell transcriptomics and spatial locations to accurately organize spatial 3 trajectory is remaining challenges. Here we introduce spaTrack, a trajectory …

  6. Spatial transition tensor of single cells - Nature Methods

    May 16, 2024 · Spatial transcriptomics measures additional spatial information at individual cells or spots of a small group of cells, allowing analysis of heterogenous cell states in space 16, 17.

  7. Inferring histology-associated gene expression gradients in spatial ...

    Aug 23, 2024 · Traditional approaches in spatial transcriptomics often rely on preliminary data grouping, which can overlook subtle expression patterns in tissues. Here, the authors present Spatial Gradient ...

  8. Single-cell and spatial transcriptomics analysis of non-small ... - Nature

    May 23, 2024 · Myeloid cell populations play a critical role in lung cancer progression. Here, the authors use scRNA-seq and spatial transcriptomics to identify changes in the phenotype of macrophages …

  9. Accurate trajectory inference in time-series spatial transcriptomics ...

    Mar 19, 2025 · Most tissues contain spatially contiguous regions that develop as a unit, such as follicles in the ovary, or tubules and glomeruli in the kidney. We find that existing approaches designed to use …

  10. 空间转录组教程|| stLearn :空间轨迹推断 - 简书

    Dec 17, 2020 · spatial trajectory inference : 这部分是此演示文本的重点,我们将在下面描述之。 spatial cell-cell interactions: 为了研究细胞-细胞相互作用 (CCI),stLearn将细胞类型多样性和L-R共表达结 …